Nanoparticle activated Neutrophils-on-a chip: A label-free capacitive sensor to monitor cells at work

Kalle Bunnfors,Natalia Abrikossova,Joni Kilpijärvi,Peter Eriksson,Jari Juuti,Niina Halonen,Caroline Brommesson,Anita Lloyd Spetz,Kajsa Uvdal

Sensors and Actuators B: Chemical（2020）

引用 7|浏览23

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摘要

•Sensor monitoring cellular ROS burst in time frames of minutes.•CMOS is combined with LTCC technology.•Lable free capacitive response by cells on an insulating surface in a weak electromangnetic field.•Cell activity in response to external triggers, in this case nanoparticles is measured.

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关键词

Complementary metal oxide semiconductor (CMOS),Low temperature co-fired ceramic (LTCC) packaging,Lab-on-a-chip,Neutrophil granulocytes,Capacitive sensor,Cerium oxide nanoparticles

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