INFLAMMATION AND EXERCISE INTOLERANCE IN HEART FAILURE WITH PRESERVED EJECTION FRACTION

Emily Lau,Shahrooz Zarbafian, Ruslan Ilyasovich,John Sbarbaro,Robyn Farrell,Mark Schoenike,Rajeev Malhotra,Susan Cheng,Mohit Jain,Gregory D. Lewis,Jennifer Ho

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2020）

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摘要

Inflammation has been implicated in the pathobiology of HFpEF. We examined the association of upstream mediators of inflammation as ascertained by eicosanoid metabolites, with exercise manifestations of HFpEF. We studied 516 participants (mean age 57, 62% women) with chronic dyspnea and preserved

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