A review of the research progress in T-lymphocyte immunity and cervical cancer

TRANSLATIONAL CANCER RESEARCH(2020)

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摘要
Cervical cancer develops as a result of T-cell immune evasion by human papillomavirus (HPV). T- cell immunity requires the participation of many factors, such as antigen-presenting cells ( APCs), cytokines, co-stimulatory molecules, etc. HPV vaccines are promising treatments to prevent HPV infection and cervical cancer. This article mainly provides a summary of the number and function changes of T cells during HPV infection and cervical cancer development. Studies on t-cell immunotherapy, which is expected to become a new treatment for cervical cancer after surgery, radiotherapy, and chemotherapy, are also reviewed in this article.
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关键词
T-cell,cervical cancer,human papillomavirus (HPV),immunotherapy
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