Cytotoxicity and hemostatic activity of chitosan/carrageenan composite wound healing dressing for traumatic hemorrhage

Carbohydrate Polymers(2020)

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Abstract
•Polysaccharide based hemostatic dressing was successfully fabricated.•The dressing was fabricated via ionic complexation and freeze-drying, without any cross-linking agent.•Mesoporous chitosan/carrageenan composite dressing had faster blood clotting ability.•Composite dressing showed good biocompatibility and in vitro cell proliferation for wound healing.•Biological studies confirmed the hemostatic activity of the developed dressing.
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Key words
Chitosan,Carrageenan,Hemostasis,Cell proliferation,Thrombin generation
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