Stereoselective Reduction Of Bisdemethoxycurcumin To (R)-Hexahydrobisdemethoxycurcumin By Cultured Moms Bombycis Plant Cells

Kei Shimoda,Naoji Kubota,Hiroki Hamada, Kouki Kawakami,Noriyuki Nakayama,Hatsuyuki Hamada

NATURAL PRODUCT COMMUNICATIONS（2020）

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摘要

Biotransformation of bisdemethoxycurcumin was examined using cultured plant cells of Morus bombycis, the Moraceae mulberry family, as biocatalysts. The cultured cells converted bisdemethoxycurcumin into (R)-hexahydrobisdemethoxycurcumin in 30% yield in 1 day. The (S)-stereoisomer has been isolated from Betula platyphylla Sukatchev var. japonica.

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关键词

stereoselective reduction,cultured plant cells,Morus bombycis,bisdemethoxycurcumin,(R)-hexahydrobisdemethoxycurcumin

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