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SnapShot: Cancer-Associated Fibroblasts

Danielle Park,Erik Sahai,Antonio Rullan

CELL（2020）

Cited 94|Views8
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Abstract
Cancer-associated fibroblasts (CAFs) are an integral component of the tumor microenvironment and have both tumor-promoting and tumor-suppressive functions. This SnapShot summarizes the origins of CAFs, their diverse functions, and how this relates to heterogeneity within the population. The suitability of targeting CAFs therapeutically is also discussed.
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