Directed Evolution of Adenine Base Editors with Increased Activity and Therapeutic Application

Nicole M. Gaudelli,Dieter K. Lam,Holly A. Rees, Noris M. Solá-Esteves,Luis A. Barrera,David A. Born,Aaron Edwards,Jason M. Gehrke,Seung-Joo Lee,Alexander J. Liquori,Ryan Murray,Michael S. Packer,Conrad Rinaldi,Ian M. Slaymaker,Jonathan Yen, Lauren E. Young,Giuseppe Ciaramella

Nature Biotechnology（2020）

引用 323|浏览39

关键词

Protein design,Recombinant protein therapy,Life Sciences,general,Biotechnology,Biomedicine,Agriculture,Biomedical Engineering/Biotechnology,Bioinformatics

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