Central diabetes insipidus related to anti-programmed cell-death 1 protein active immunotherapy

International Immunopharmacology(2020)

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Abstract
•Our patient is the first case of nivolumab related central diabetes insipidus.•Hypovolemic hypernatremia can be rare manifestation of central diabetes insipidus.•Nivolumab can rarely be associated with immune related hypophystis.•Central diabetes insipidus is rare in the context of immune related hypophysitis.
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Key words
Central diabetes insipidus,Hypophysitis,Hypernatremia,Nivolumab,Immunotherapy
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