Effect of N-substituent in 4-styrylpyridinium dyes on their binding to DNA

Maria A. Ustimova, Polina A. Chernikova,Nikolai E. Shepel,Yury V. Fedorov,Olga A. Fedorova

Mendeleev Communications（2020）

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摘要

4-Styrylpyridinium dyes containing N-methyl and N-(3-pyridiniopropyl) substituents have been prepared and characterized by optical and CD spectroscopy. These compounds demonstrate affinity to calf thymus DNA, with dye–DNA binding mode being different for various N-substituents.

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关键词

styryl dye,DNA,intercalation,groove binding,fluorescent probes

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