Local effect of simvastatin combined with different osteoconductive biomaterials and collagen sponge on new bone formation in critical defects in rat calvaria.

Dircilei Nascimento de Sousa,Virgílio Moreira Roriz,Guilherme José Pimentel Lopes de Oliveira,Wagner Rodrigues Duarte, Leonardo Nogueira de Miranda Pereira Pinto,Leonora Maciel de Souza Vianna,Fabiana Pirani Carneiro,Vania Maria Moraes Ferreira

Acta cirurgica brasileira（2020）

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摘要

The use of SVT without the need for a vehicle and combined with a commercially available biomaterial may be a cheaper way to potentiate the formation of bone tissue without the need to produce new biomaterials. Therefore, SVT combined with DBB induced significantly greater new bone formation than did the other treatments.

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关键词

Biocompatible Materials,Bone Regeneration,Simvastatin,Rats

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