Two new 7, 20-epoxy-ent-kauranes from the aerial parts of Isodon eriocalyx
Natural Product Research(2020)
Abstract
Two previously undescribed 7, 20-epoxy-ent-kauranes along with six known ent-kauranoids, were isolated from the aerial parts of Isodon eriocalyx. The structures of new compounds were established on the basis of extensive spectroscopic analyses. Compound 2 could inhibit the production of interleukin - 1β (IL - 1β) in monosodium urate (MSU) and lipopolysaccharide (LPS) induced macrophages.
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Key words
Isodon eriocalyx,7,20-epoxy-ent-kaurane,anti-inflammatory activity,interleukin - 1β
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