We report the first detection of coherent elastic neutrino-nucleus scattering (CEvNS) on argon using the CENNS-10 liquid argon detector at the Oak Ridge National Laboratory Spallation Neutron Source. Two independent analyses prefer CEvNS over the background-only null hypothesis with greater than $3\sigma$ significance. The measured cross section, averaged over the incident neutrino flux, is (2.2 $\pm$ 0.7) $\times$10$^{-39}$ cm$^2$ --- consistent with the standard model prediction. This is the lightest nucleus for which CEvNS has been observed, which allows us to verify the expected neutron-number dependence of the cross section and to better constrain non-standard neutrino interactions.
