Comparing intentions to reduce substance use and willingness to seek help among transgender and cisgender participants from the global drug survey

•Cis men were more likely than cis women to want to reduce alcohol and cannabis use.•The desire to reduce substance use did not differ between trans and cis participants.•Among those who wanted to use less, trans people were more likely to want help.•Non-binary people most often reported a need for help to use reduce alcohol and cannabis use.•Trans women most frequently reported a desire for help to reduce illicit drug use.