Hiding in Plain Sight: an Approach to Treating Patients with Severe COVID-19 Infection.

David S Fedson,Steven M Opal, Ole Martin Rordam

MBIO（2020）

引用 152|浏览31

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摘要

Patients with COVID-19 infection are at risk of acute respiratory disease syndrome (ARDS) and death. The tissue receptor for COVID-19 is ACE2, and higher levels of ACE2 can protect against ARDS. Angiotensin receptor blockers and statins upregulate ACE2. Clinical trials are needed to determine whether this drug combination might be used to treat patients with severe COVID-19 infection.

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关键词

COVID-19,endothelial dysfunction,generic drugs,host response treatment

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