A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by endoplasmic reticulum aminopeptidase 1
Journal of Biological Chemistry（2020）
关键词
major histocompatibility complex (MHC),aminopeptidase,antigen processing,antigen presentation,enzyme mechanism,transition-state analog,biophysics,enzyme kinetics,endoplasmic reticulum (ER),immunogenicity,ERAP1,ERAP2,HLA,MALDI,peptide,trimming mechanism,adaptive immunity,cytotoxic T lymphocyte,immunogenicity regulation
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