In vivo effect of minocycline alone and in combination with immunotherapy against pythium insidiosum

Carine E.P. Zimmermann, Francielli P.K. Jesus,Karine B. Schlemmer, Érico S. Loreto,Juliana S.M. Tondolo, David Driemeier,Sydney H. Alves, Laerte Ferreiro,Janio M. Santurio

Veterinary Microbiology（2020）

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摘要

•Minocycline has fungistatic activity against Pythium insidiosum.•Minocycline in combination with immunotherapy is an effective treatment strategy for pythiosis.•Pitium-Vac® plus minocycline combination therapy can cure pythiosis.

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关键词

Pythiosis,Minocycline,Fungistatic activity,Immunotherapy,Pitium-Vac®

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