Preparation of poly(glutamic acid) shielding micelles self-assembled from polylysine-b-polyphenylalanine for gene and drug codelivery

Chinese Chemical Letters(2020)

Cited 19|Views11
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Abstract
A novel gene and drug codelivery system based on amphiphilic cationic block copolymer polylysine-b-polyphenylalanine shielded with poly(glutamic acid) (PG/PLL-b-PPhe) was prepared to perform combinational cancer therapy
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Key words
Codelivery,Shielding,Doxorubicin,Bcl2 siRNA,Cancer therapy
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