L-amino acid ligase: A promising alternative for the biosynthesis of L-dipeptides
Enzyme and Microbial Technology(2020)
摘要
•l-amino acid ligases (Lals) are desirable tools for the catalytic biosynthesis of dipeptides of industrial importance.•Studies on the substrate reorganization mechanisms are critical for engineering of Lals with desired properties.•It is extremely important to improve the catalytic performance and substrate specificity of Lals simultaneously.
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关键词
L-amino acid ligase,Biosynthesis,Dipeptides,Substrate specificity,Protein engineering
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