Time-dependent effects of cellulose and gelatin-based hemostats on cellular processes of wound healing.

Markus U Wagenhäuser,Waseem Garabet, Mia van Bonn,Wiebke Ibing,Joscha Mulorz, Yae Hyun Rhee,Joshua M Spin,Christos Dimopoulos,Alexander Oberhuber,Hubert Schelzig,Florian Simon

Archives of medical science : AMS（2023）

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摘要

Short-term exposure to ORC and ONRC impairs relevant wound healing-related processes in fibroblasts, and alters protein levels of key mediating cytokines. GELA does not show similar effects. We conclude that GELA may be preferred over ORC and ONRC over short-, intermediate- and long-term exposures. Future validation of the clinical relevance is warranted.

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关键词

cell migration,cell proliferation,cellulose,cytokine,exposure,fibroblast,gelatin,hemostats,wound healing

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