Protective effects of polymethoxyflavone-rich cold-pressed orange peel oil against ultraviolet B-induced photoaging on mouse skin

Guijie Li,Fang Tan,Qunlin Zhang,Anqun Tan,Yujiao Cheng,Qi Zhou, Manjiao Liu,Xiang Tan,Linhua Huang,Russell Rouseff,Houjiu Wu,Xin Zhao,Guolu Liang,Xiaochun Zhao

Journal of Functional Foods（2020）

Cited 13|Views13

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Abstract

•Orange cold-pressed oil (CPO) protects mouse skin from UVB-induced oxidative damage.•CPO helps to maintain collagen normality by regulating TIMP 1&2 and MMP 2&9.•5-hydroxy products found as UVB degradation of topical polymethoxyflavones (PMFs).•PMFs and hydroxy-PMFs play important part in the anti-photoaging effects of CPO.

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Key words

CPO,PMF,OH-PMF,UVR,THF,MED,DAD,SOD,CAT,GSH-Px,MDA,IL,TNF,Col,MMP,TIMP,H&E,ECM,SIN,HEX,NOB,TET,HEP,TAN,OH-NOB,OH-TAN

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