Phase I Results Of The Phase I/Ii Study Of Pembrolizumab In Combination With Binimetinib In Patients With Unresectable Locally Advanced Or Metastatic Triple-Negative Breast Cancer

Saranya Chumsri,Mei-Yin Polley, Pulkit Mathur,Aline Reis,Kathleen S. Tenner,Morgan Weidner,Pooja Advani,Alvaro Moreno-Aspitia,Edith A. Perez,Keith L. Knutson

JOURNAL OF CLINICAL ONCOLOGY（2020）

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78Background: Previous study demonstrated that activation of RAS/MAPK pathway is associated with reduced tumor infiltrating lymphocytes and poor response to neoadjuvant chemotherapy in triple negat...

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