A Phase Ii Study Investigating Cabozantinib In Patients With Refractory Metastatic Colorectal Cancer (Agicc 17crc01)

Aaron James Scott,Steven J. Cohen,Atrayee Basu Mallick,Efrat Dotan,Philip Jordan Gold,Howard S. Hochster,Somasundaram Subramaniam,Afsaneh Barzi,Patrick Jud Blatchford,Wells A. Messersmith

JOURNAL OF CLINICAL ONCOLOGY（2020）

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摘要

103Background: Therapeutic resistance to antiangiogenics in metastatic colorectal cancer (mCRC) inevitably develops via multiple mechanisms including upregulation of the MET kinase pathway. Cabozan...

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关键词

refractory metastatic colorectal cancer,cabozantinib,colorectal cancer

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