Single-Photon Emission Computed Tomography Imaging Using Formyl Peptide Receptor 1 Ligand Can Diagnose Aortic Aneurysms in a Mouse Model.

Alexander H Shannon,Mahendra D Chordia, Michael D Spinosa,Gang Su,Zachary Ladd,Dongfeng Pan,Gilbert R Upchurch,Ashish K Sharma

Journal of Surgical Research（2020）

引用 12|浏览7

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摘要

cFLFLF, a novel FPR1 ligand, enables quantifiable, noninvasive diagnosis and progression of AAAs. Clinical application of this inflammatory, cell-specific molecular probe using SPECT imaging may permit early diagnosis of AAA formation, enabling targeted therapeutic interventions and preventing impending aortic rupture.

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关键词

Vascular imaging,SPECT scans,Formyl peptide receptor,Abdominal aortic aneurysms,Aortic inflammation

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