Serologic Detection of Middle East Respiratory Syndrome Coronavirus Functional Antibodies.

Nisreen M A Okba,Ivy Widjaja,Wentao Li,Corine H GeurtsvanKessel,Elmoubasher A B A Farag,Mohammed Al-Hajri,Wan Beom Park,Myoung-Don Oh,Chantal B M E Reusken,Marion P G Koopmans,Berend-Jan Bosch,Bart L Haagmans

EMERGING INFECTIOUS DISEASES（2020）

引用 27|浏览45

暂无评分

摘要

We developed and validated 2 species-independent protein-based assays to detect Middle East respiratory syndrome coronavirus functional antibodies that can block virus receptor-binding or sialic acid-attachment. Antibody levels measured in both assays correlated strongly with virus-neutralizing antibody titers, proving their use for serologic confirmatory diagnosis of Middle East respiratory syndrome.

查看译文

关键词

MERS,MERS-CoV,Middle East respiratory syndrome,Middle East respiratory syndrome coronavirus,antibodies,dromedary,hemagglutination,human,lumazine synthase,nanoparticle,neutralization,respiratory infections,serology,spike,viruses,zoonoses

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要