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Bioinformatical Analysis of Gene Expression Omnibus Database Associates TAF7/CCNB1, TAF7/CCNA2, and GTF2E2/CDC20 Pathways with Glioblastoma Development and Prognosis

Liangwang Yang,Wangyuan Zeng,Huamao Sun,Fen Huang,Changcheng Yang,Xingrui Cai,Yanda Lu,Jiangzheng Zeng, Kun Yang

WORLD NEUROSURGERY（2020）

Cited 19|Views84
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Abstract
This study revealed several DEGs in glioblastoma, and aberrant expression of their hub genes was associated with glioblastoma pathogenesis and poor prognosis, especially the signaling axes of TAF7/CCNB1, TAF7/CCNA2, and GTF2E2/CDC20.
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Key words
CGGA,GEO,TCGA,bioinformatical analysis,differentially expressed genes,glioblastoma,transcriptional factors
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