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In the rat pancreas, somatostatin tonically inhibits glucagon secretion and is required for glucose-induced inhibition of glucagon secretion.

Stella F S Xu,Daniel B Andersen,Jose M G Izarzugaza,Rune E Kuhre,Jens J Holst

Acta physiologica (Oxford, England)（2020）

Cited 29|Views14
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Abstract
Somatostatin is a powerful and tonic inhibitor of glucagon secretion from the rat pancreas and is required for glucose to inhibit glucagon secretion.
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Key words
GABA,Glucagon secretion,Insulin,Intrinsic regulation,Isolated perfused rat pancreas,Paracrine regulation,Somatostatin
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