Hyperacmosins E-G, three new homoadamantane-type polyprenylated acylphloroglucinols from Hypericum acmosepalum.
Fitoterapia(2020)
摘要
Three new homoadamantane-type polyprenylated acylphloroglucinols, hyperacmosins E-G (1–3), with seven known compounds were isolated from the air-dried aerial parts of Hypericum asmosepalum. Their structures were determined by NMR, HRESIMS and experimental electronic circular dichroism (ECD) spectra. The hepatoprotective activity of these compounds were evaluated. Compounds 4 and 8 exhibited hepatoprotective activity against paracetamol-induced HepG2 cell damage.
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关键词
Hypericum acmosepalum,PPAPs,Homoadamantane-type,Hepatoprotective
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