Characterization of the main immunogenic proteins in Brucella infection for their application in diagnosis of brucellosis.

Mingxing Tian,Meiying Song,Yi Yin,Zhengmin Lian,Zichen Li,Hai Hu,Xiang Guan,Yumei Cai,Chan Ding,Shaohui Wang,Tao Li,Jingjing Qi,Shengqing Yu

Comparative Immunology, Microbiology and Infectious Diseases（2020）

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摘要

•Antibody production rule of immunogenic proteins was drawn in Brucella infection.•The BP26 and BLS proteins were two best immunogenic proteins.•It is unsuitable for BP26 and BLS as diagnostic antigens due to false-positive result.

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关键词

Brucellosis,Antibody production,Immunogenic protein,Diagnosis

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