Flash vacuum pyrolysis of acetylenic amides: A mechanistic study

Nouria A. Al-Awadi,Asaad S. Mohamed,Osama M. Habib,Fatma H. Al-Awadhi,Nader A. Al-Jalal,Yehia A. Ibrahim

Journal of Analytical and Applied Pyrolysis（2020）

引用 4|浏览25

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摘要

•Synthetic application of FVP of acetylenic amides for 1-azazzulene-2-ones and unsaturated lactams.•Two independent process are involved: retro-ene reaction and carbene intermediate.•Alkyne functionality provides antiproliferative activity.

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关键词

FVP,Acetylenic amides,Reaction mechanisms,Carbene intermediate,Biological activity

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