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Synthesis of pyrrolo[3,4-d]isoxazolines via a one-pot radical functionalization/cycloaddition of methyl ketone, tert-butyl nitrite, and maleimide

Hang Wang,Rui Cheng,Gangqiang Wang,Yang Shi,Jian Wang,Haibing Guo,Leslie Trigoura,Yalan Xing,Shaofa Sun

Tetrahedron Letters（2020）

Cited 5|Views4
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Abstract
•Efficient synthesis of pyrrolo[3,4-d]isoxazolines.•A one-pot radical functionalization/cycloaddition.•Broad functional group tolerance and wide substrate scope.
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Key words
Cycloaddition,Pyrrolo[3,4-d]isoxazolines,Maleimide,One-pot
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