Papular eruption characteristic of persistent agmination of lymphomatoid papulosis

Inigo Martínez-de-Espronceda,Saioa Oscoz, Jorge Arostegui, Josune Mitxelena,Alicia Córdoba, Juan-Ignacio Yanguas

Journal of Hematopathology(2020)

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Abstract
A 48-year-old man presented with a 1-year history of a nontender, pruritic, well-circumscribed crop of waxing and waning papules. The histological findings were compatible with lymphomatoid papulosis (LyP) in spite of the fact that cutaneous distribution was not typical. Attending to the clinicopathological correlation, we established the diagnosis of persistent agmination of lymphomatoid papulosis (PALP). PALP is a rare variant of CD30+ primary cutaneous T cell lymphoproliferative disorder, with only a few reported cases in the literature. It is still controversial whether PALP is a subtype of localized LyP or an own entity. In any case, there is potential of developing malignancy, so at least a cautious long-term follow-up is recommended in these patients.
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Key words
Lymphomatoid papulosis,Persistent agmination,CD30+ cutaneous T cell lymphoma,Localized lymphomatoid papulosis
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