Enzyme Cascade Reaction-Based Ratiometric Fluorescence Probe for Visual Monitoring the Activity of Alkaline Phosphatase
Sensors and Actuators B: Chemical（2020）
Abstract
•A ratiometric fluorescence probe based on CdTe/CdS/ZnS/SiO2 QDs and an enzyme cascade reaction for ALP sensing.•Sensitive and selective ALP activities sensing and inhibitors screening.•Simultaneous and highly sensitive detection of ALP in human serum.•Great potential for further clinical diagnosis and drug screening.
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Key words
Visualization,Ratiometric fluorometry,Alkaline phosphatase,Inner filter effect,Inhibitors screening
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