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Proteome and miRNome profiling of microvesicles derived from medulloblastoma cell lines with stem-like properties reveals biomarkers of poor prognosis

Carolini Kaid,Amanda Assoni,Marina Marçola,Patricia Semedo-Kuriki,Raul Hernandes Bortolin,Valdemir Melechco Carvalho,Oswaldo Keith Okamoto

Brain Research（2020）

Cited 11|Views24
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Abstract
•Proteome and miRNome profiling of human medulloblastomas MVs.•464 proteins and 10 miRNAs were exclusively detected in tumor MVs.•Specific MVs factors might serve as biomarkers of stem-like medulloblastoma cells.
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Key words
Microvesicles,Medulloblastoma,OCT4A,Proteome,miRNA
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