Single-step coprecipitation and coating to prepare curcumin formulations by supercritical fluid technology

The Journal of Supercritical Fluids(2020)

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摘要
•The SAS process was combined with two configurations of fluidized beds.•Properties of fluidization in tapered beds and stirred vessels were discussed.•Curcumin/PVP coprecipitates were produced and coated on different carrier particles.•Curcumin release and flow properties were enhanced in a single-step process.
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关键词
Supercritical antisolvent,Coprecipitation,High-pressure fluidization,Coating,Process integration,Curcumin
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