Hematological and biochemical studies on hemodylitic patients at the Government General Hospital, Wadi Al-Dawaser

Background: Renal failure is a slowly progressive disease of kidney, characterized by low glomerular filtration. One of the most important replacement therapy of renal failure is hemodialysis which helping in the removal of toxic fluids and metabolic end products from the body.

Methods: This study was carried out on 43 patients with renal failure in the dialysis unit of Wadi Al-Dawaser General Hospital. Patients were 25 males and 18 females, randomly selected for the study between September and November 2018. Blood samples were obtained from all patients pre and post dialysis for serum biochemical analysis including kidney function test, liver function, lipid profile, glucose, electrolytes, while blood sample with anticoagulants collected pre dialysis for complete blood picture.

Results: The hemogram parameters recorded significant decrease while leuckogram insignificantly increase specially eosinophils, in pre-dialysis patients. Serum biochemical parameters were significantly high pre-dialysis recorded 83.7%, 97.7%, 21% for urea, creatinine and uric acid respectively, while significantly decrease post dialysis. In contrast serum glucose and magnesium levels were significantly high pre and post dialysis. As result of decrease of the erythropoietin production in chronic renal failure patients lower hematological indices, increase the risk of anemia are main results.

Conclusions: Dialysis improve the biochemical parameters of serum especially creatinine and urea while glucose and magnesium not improved.