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The selective condensation of pyrazolones to isatins in aqueous medium

Yong Zhang,Long-Jun Nie,Liang Luo, Jia-Xin Mao,Jin-Xiang Liu,Guo-Hai Xu,Deliang Chen,Hai-Qing Luo

Tetrahedron（2020）

Cited 7|Views6
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Abstract
The selective condensation of pyrazolones with isatins using water as the reaction medium is presented. This strategy provides an environmentally benign synthetic route to synthesize various potentially bioactive pyrazolone substituted oxindoles.
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Key words
Water,Condensation,Pyrazolones,Oxindoles
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