Combined effects of celecoxib and cepharanthine on human colorectal cancer cells in vitro

Parawee Lerdwanangkun,Piyanuch Wonganan, Robin James Storer,Wacharee Limpanasithikul

journal of applied pharmaceutical science（2019）

引用 24|浏览1

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摘要

Colorectal cancer is one of the most common cancers worldwide. We investigated effects of celecoxib (CLX)â€“cepharanthine (CEP) in combination on HT-29 human colorectal cancer cells. CLX at 5, 10, 20, or 40 ÂµM in combination with CEP at 1.25, 2.5, or 5 ÂµM displayed synergistic cytotoxic effects with a combination index

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