Nobel Prize in Physiology or Medicine 2019

Resonance（2019）

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摘要

The Nobel Prize in Physiology or Medicine, 2019 was awarded jointly to William G. Kaelin Jr. of Dana-Farber Cancer Institute, Sir Peter J. Ratcliffe of Francis Crick Institute and University of Oxford and Gregg L. Semenza of Johns Hopkins University for their discovery of how cells sense and respond to varying oxygen levels.

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关键词

Hypoxia, normoxia, hypoxia inducible factor (HIF), hypoxia responsive element (HRE), angiogenesis, erythropoietin (EPO), HIF-prolyl hydroxylase, von Hippel Lindau (VHL)

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