ORAL AMYLOIDOSIS: 2 CASE REPORTS

Amyloidosis refers to extracellular and progressive deposition of the fibrillar protein that can be localized or generalized. In the head and neck region, amyloidosis is uncommon. When it occurs in the mouth, the tongue is the most affected site. The present study reports 2 cases of male patients who attended the stomatology clinic to investigate oral lesions without diagnosis. The first one at 60 years old and no systemic alterations presented an increase in submandibular, sublingual glands, and papular lesions in the bilateral buccal mucosa and tongue. A radiographic examination confirmed sialectasis in the submandibular gland. The second one at 82 years old and several systemic alterations, such as red and white series deregulation, diabetes, high levels of amylase, uranium, and creatinine among others, presented multiple papules in the tongue. In both cases, an incisional biopsy was performed, and the histopathologic examination confirmed amyloidosis. The patients continue to be monitored.