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Pomegranate peel extract ameliorates liver fibrosis induced by carbon tetrachloride in rats through suppressing p38MAPK/Nrf2 pathway

Xianglan Wei,Siyao Li,Tingting Li,Longzhu Liu, Yuan Liu,Hao Wang,Yong Zhou,Fanfan Liang,Xiaojiang Yu,Weijin Zang,Ming Zhao,Zhenghang Zhao

Journal of Functional Foods（2020）

Cited 14|Views34
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Abstract
•EPP displays a protective effect against liver fibrosis induced by CCl4 in rat.•EPP has an antioxidative effect on the CCl4 injury liver of rat.•Underlying mechanisms might be associated with suppressing p38MAPK/Nrf2 signaling.
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Key words
Pomegranate peel extract,Liver fibrosis,p38MAPK-Nrf2 pathway,Carbon tetrachloride
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