Inflammatory pseudotumor-like follicular dendritic cell sarcoma: A brief report of two cases.
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY(2019)
Abstract
BACKGROUND Follicular dendritic cell (FDC) sarcoma/tumor is a rare malignant tumor of follicular dendritic cells, which is considered a low-grade sarcoma that can involve lymph nodes or extranodal sites. Conventional FDC sarcomas are negative for Epstein-Barr virus (EBV), whereas the inflammatory pseudotumorlike variant consistently shows EBV in the neoplastic cells. CASE SUMMARY We report two cases of inflammatory pseudotumor-like FDC sarcoma in the liver that received 3D laparoscopic right hepatectomy and open right hepatectomy separately. CONCLUSION EBV probe-based in situ hybridization and detection of immunohistochemical markers of FDC play an important role in the diagnosis and differential diagnosis of inflammatory pseudotumor-like FDC sarcoma. Complete surgical excision combined with regional lymphadenectomy may be effective in reducing the postoperative recurrence and metastasis and improving long-term survival rates.
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Key words
Inflammatory pseudotumor-like follicular dendritic cell sarcoma,Epstein-Barr virus,Liver,Spleen,Case report
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