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Coarse-Grained Molecular Dynamics Simulations for Understanding the Impact of Short-Range Anisotropic Attractions on Structure and Viscosity of Concentrated Monoclonal Antibody Solutions.

Molecular pharmaceutics(2020)

Cited 29|Views34
Key words
antibody,high concentration,protein-protein interactions,small-angle X-ray scattering,structure factor,coarse-grained modeling,molecular dynamics simulations,self-association,viscosity
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