[Impact of the Epstein Barr virus on gastric cancer in Peru].
Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru(2019)
摘要
Epstein Barr Virus (EBV) is responsible of 10% of Gastric Cancer (GC), correlating with better survival rates. In Peru, there were not studies about prevalence and clinical characteristics of CG EBV positive.
OBJECTIVE:Determine prevalence and clinicopathological characteristics of GC EBV positive.
MATERIALS AND METHODS:111 GC tumour samples were centrally screened by Chromogenic in situ hybridization (CISH) technique for EBV-encoded RNA (EBER) transcript.
RESULTS:8.4% of cases were positive for EBV. Most cases EBV positive were more than 60 years old; male, antrum/pylorus had more frequent localizations. Most cases had an intestinal type and tubular patter and a tendency to better prognostic in comparison EBV negative cases.
CONCLUSION:EBV positive GC is an entity with a prevalence of 8.4% in Peru with distinctive clinical and morphological characteristics.
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