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Combination of PI3K and MEK Inhibitors Yields Durable Remission in PDX Models of PIK3CA-mutated Metaplastic Breast Cancers

F. Coussy,R. El Botty, M. Lavigne, C. Gu,L. Fuhrmann,A. Briaux,L. de Koning,A. Dahmani, E. Montaudon, L. Morisset, L. Huguet, L. Sourd, P. Painsec,S. Chateau-Joubert,T. Larcher,S. Vacher,S. Melaabi,A. Vincent Salomon,E. Marangoni,I. Bieche

Journal of Hematology & Oncology（2020）

Cited 37|Views59
Key words
Metaplastic breast cancer,PI3K inhibitor,MEK inhibitor,Combination of targeted therapies
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