Polyoxazolines Based Lipid Nanocapsules for Topical Delivery of Antioxidants.

•Innovative PEG free lipid nanocapsules made of an oily core surrounded by a phospholipid and polyoxazoline shell.•Stable nanoformulations loaded with quercetin, a natural antioxidant.•Lipid nanocapsules stabilized by polyoxazoline successfully led to higher drug loading than the original one with PEG.•Powerful antioxidant activity of polyoxazoline based lipid nanocapsules on human keratinocytes after UV exposure.