N,N-Dimethyltryptamine Reduces Infarct Size And Improves Functional Recovery Following Transient Focal Brain Ischemia In Rats

Experimental Neurology(2020)

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摘要
Our results indicate a Sig-1R dependent reduction of the ischemic brain injury following exogenous DMT administration in rats, presumably through a combined anti-apoptotic, pro-neurotrophic and anti-inflammatory treatment effect.
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关键词
N,N-dimethyltryptamine,Middle cerebral artery occlusion,Neuroprotection,Inflammation,Sigma 1 receptor
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