Sodium tanshinone IIA sulfonate protects against acute exacerbation of cigarette smoke-induced chronic obstructive pulmonary disease in mice.

Defu Li,Dejun Sun,Liang Yuan,Chunli Liu,Lingzhu Chen,Guihua Xu,Jiaze Shu,Ruijuan Guan,Jingyi Xu,Yuanyuan Li,Gao Yi,Hongwei Yao,Nanshan Zhong,Jian Wang,Wenju Lu

International Immunopharmacology（2020）

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摘要

•STS protected against acute exacerbation of CS-induced COPD in mice.•STS attenuated inflammatory responses in CSE-treated 16HBE challenged with LPS.•STS may provide a promising therapeutic avenue for acute exacerbation of COPD.

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关键词

COPD,STS,Acute exacerbation,Cigarette smoke

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