Transcriptional Correlates of Tolerance and Lethality in Mice Predict Ebola Virus Disease Patient OutcomesWOS

    Adam Price
    Adam Price
    Atsushi Okumura
    Atsushi Okumura
    Kimberly Meade-White
    Kimberly Meade-White
    Pryanka Sharma
    Pryanka Sharma
    Methinee Artami
    Methinee Artami
    Angela L Rasmussen
    Angela L Rasmussen
    Cited by: 0|Bibtex|13|

    Cell reports, pp. 17022020.

    Keywords:
    Collaborative CrossEbolaclassificationhost responsepathogenesisview more (3+)

    Abstract:

    Host response to infection is a major determinant of disease severity in Ebola virus disease (EVD), but gene expression programs associated with outcome are poorly characterized. Collaborative Cross (CC) mice develop strain-dependent EVD phenotypes of differential severity, ranging from tolerance to lethality. We screen 10 CC lines and id...More
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