Knockdown of enhancer of rudimentary homolog inhibits proliferation and metastasis in ovarian cancer by regulating epithelial-mesenchymal transition.
Biomedicine & Pharmacotherapy(2020)
Abstract
•The ERH expression level is high in ovarian cancer.•Patients with ovarian cancer with high expression of ERH have a poor prognosis.•Knockdown of ERH could inhibit proliferation and promotes apoptosis in ovarian cancer cells.•ERH can promote the metastasis of ovarian cancer by regulating EMT.•ERH has potential as a molecular therapeutic target for ovarian cancer.
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Key words
Ovarian cancer,Proliferation,Nhancer of rudimentary homolog (ERH),Epithelial-mesenchymal transition (EMT)
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