Differential expression of lncRNAs during silicosis and the role of LOC103691771 in myofibroblast differentiation induced by TGF-β1.
Biomedicine & Pharmacotherapy(2020)
Abstract
•A total of 306 LncRNAs were altered in a chronic silicotic model.•Several LncRNAs had similar changes in TGF-β1-treated lung fibroblasts.•LOC103691771 promoted myofibroblast differentiation by TGF-β1/Smad signaling.
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Key words
Silicosis,lncRNA,Fibroblast,Myofibroblast,LOC103691771
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