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Differential expression of lncRNAs during silicosis and the role of LOC103691771 in myofibroblast differentiation induced by TGF-β1.

Wenchen Cai,Hong Xu,Bonan Zhang,Xuemin Gao,Shumin Li,Zhongqiu Wei,Shifeng Li,Na Mao,Fuyu Jin,Yaqian Li,Heliang Liu,Fang Yang

Biomedicine & Pharmacotherapy（2020）

Cited 18|Views19
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Abstract
•A total of 306 LncRNAs were altered in a chronic silicotic model.•Several LncRNAs had similar changes in TGF-β1-treated lung fibroblasts.•LOC103691771 promoted myofibroblast differentiation by TGF-β1/Smad signaling.
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Key words
Silicosis,lncRNA,Fibroblast,Myofibroblast,LOC103691771
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